RNS Number : 3423Y<fipBR>

Synergy Healthcare PLC<fipBR>

04 July 2008<fipBR>

<fipBR> <fipP><fipBR> TR-1: notification of major interests in shares <fipBR> </fipP>

1. Identity of the issuer or the underlying Synergy Healthcare PLC<fipBR>

issuer of existing shares to which voting<fipBR>

rights are attached:<fipBR>

2. Reason for the notification (please tick the appropriate box or<fipBR>

boxes)<fipBR>

An acquisition or disposal of voting rights <fipBR>

An acquisition or disposal of financial instruments which may result<fipBR>

in the acquisition of shares already issued to which voting rights<fipBR>

are attached<fipBR>

An event changing the breakdown of voting rights<fipBR>

Other (please specify): <fipBR>

3. Full name of person(s) subject to the Newton Investment Management Limited<fipBR>

notification obligation:<fipBR>

4. Full name of shareholder(s) (if different<fipBR>

from 3.):<fipBR>

5. Date of the transaction (and date on which 02/07/08<fipBR>

the threshold is crossed or reached if<fipBR>

different):<fipBR>

6. Date on which issuer notified: 03/07/08<fipBR>

7. Threshold(s) that is/are crossed or Increase from 5.41% to 6.12% <fipBR>

reached:<fipBR>

8. Notified details: Transfer in of 377,519 shares<fipBR> <fipP><fipBR> </fipP> <fipP><fipBR> </fipP> <fipP><fipBR> </fipP> <fipP><fipBR> </fipP> <fipP><fipBR> </fipP> <fipP><fipBR> </fipP> <fipP><fipBR> </fipP> <fipP><fipBR> </fipP>

A: Voting rights attached to shares<fipBR>

Class/type of shares Situation previous to the Triggering Resulting situation after the triggering transaction<fipBR>

if possible using transaction <fipBR>

the ISIN CODE<fipBR>

Number of Shares Number of Voting Number of shares Number of voting % of voting<fipBR>

Rights viii rights ix rights<fipBR>

Direct Direct x Indirect xi Direct Indirect<fipBR>

Ordinary Shares 2,884,284 5.41% N/A N/A 3,261,803 N/A 6.12%<fipBR>

ISIN GB0030757263<fipBR> <fipBR> <fipP><fipBR> </fipP>

B: Financial Instruments<fipBR>

Resulting situation after the triggering transaction xii<fipBR>

Type of financial instrument Expiration date xiii Exercise/ Conversion Number of voting % of voting rights<fipBR>

Period/ Date xiv rights that may be<fipBR>

acquired if the<fipBR>

instrument is<fipBR>

exercised/<fipBR>

converted. <fipBR>

<fipBR> <fipP><fipBR> </fipP>

Total (A+B)<fipBR>

Number of voting rights % of voting rights<fipBR>

3,261,803 6.12%<fipBR> <fipP><fipBR> </fipP> <fipP><fipBR> </fipP> <fipP>`</fipP> <fipP><fipBR> </fipP> <fipP><fipBR> </fipP> <fipP><fipBR> </fipP> <fipP><fipBR> </fipP> <fipP><fipBR> </fipP>

9. Chain of controlled undertakings through which the voting rights and/or<fipBR>

the financial instruments are effectively held, if applicable xv:<fipBR>

Newton Investment Management Limited hold these shares as a discretionary<fipBR>

Investment Manager.<fipBR> <fipP><fipBR> </fipP>

Proxy Voting:<fipBR>

10. Name of the proxy holder: N/A<fipBR>

11. Number of voting rights proxy holder will cease to hold: N/A <fipBR>

12. Date on which proxy holder will cease to hold voting rights: N/A <fipBR> <fipP><fipBR> </fipP>

13. Additional information: <fipBR>

14. Contact name: Asif S Lalani<fipBR>

15. Contact telephone number: +44 (0)20 7163 5115<fipBR> <fipP>Annex Notification Of Major Interests In Shares xvi</fipP>

A: Identity of the person or legal entity subject to the notification obligation<fipBR>

Full name (including legal form for legal entities) Newton Investment Management Ltd <fipBR>

Contact address (registered office for legal entities) Mellon Financial Centre<fipBR>

160 Queen Victoria Street<fipBR>

London EC4V 4LA<fipBR>

Phone number +44 (0)207 163 9000 <fipBR>

Other useful information (at least legal representative for legal Rachel Wheeler<fipBR>

persons)<fipBR> <fipP><fipBR>

</fipP>

B: Identity of the notifier, if applicable xvii<fipBR>

Full name Newton Investment<fipBR>

Management Ltd <fipBR>

Contact address Mellon Financial<fipBR>

Centre<fipBR>

160 Queen Victoria<fipBR>

Street<fipBR>

London EC4V 4LA <fipBR>

Phone number +44 (0)207 163<fipBR>

9000 <fipBR>

Other useful information (e.g. functional Discretionary<fipBR>

relationship with the person or legal entity Investment Manager <fipBR>

subject to the notification obligation)<fipBR> <fipP><fipBR>

</fipP>

C: Additional information<fipBR> <fipBR> <fipP><fipBR> </fipP> <fipP>Notes </fipP> <fipBR> This information is provided by RNS<fipBR> The company news service from the London Stock Exchange<fipBR>

<fipBR>

END <fipBR>

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